Comparison of Monte Carlo methods for fluorescence molecular tomography-computational efficiency

Comparison of Monte Carlo methods for fluorescence molecular tomography-computational efficiency.

PURPOSE The Monte Carlo method is an accurate model for time-resolved quantitative fluorescence tomography. However, this method suffers from low computational efficiency due to the large number of photons required for reliable statistics. This paper presents a comparison study on the computational efficiency of three Monte Carlo-based methods for time-domain fluorescence molecular tomography. ...

Micro-computed tomography-guided, non-equal voxel Monte Carlo method for reconstruction of fluorescence molecular tomography.

The study of dual-modality technology which combines microcomputed tomography (micro-CT) and fluorescence molecular tomography (FMT) has become one of the main focuses in FMT. However, because of the diversity of the optical properties and irregular geometry for small animals, a reconstruction method that can effectively utilize the high-resolution structural information of micro-CT for tissue ...

Comparison of Regularization Methods in Fluorescence Molecular Tomography

In vivo fluorescence molecular tomography (FMT) has been a popular functional imaging modality in research labs in the past two decades. One of the major difficulties of FMT lies in the ill-posed and ill-conditioned nature of the inverse problem in reconstructing the distribution of fluorophores inside objects. The popular regularization methods based on L, L and total variation (TV ) norms hav...

Strategies for Improving the Efficiency of Monte-Carlo Methods

Multicanonical methods, molecular dynamics, and Monte Carlo methods: Comparison for Lennard-Jones glasses

We applied a multicanonical algorithm to a two-dimensional and a three-dimensional Lennard-Jones system with quasicrystalline and glassy ground states. Focusing on the ability of the algorithm to locate low-lying energy states, we compared the results of the multicanonical simulations with standard Monte Carlo simulated annealing and molecular-dynamics methods. We find slight benefits to using ...